Clinical analysis of 29 cases of pregnancy complicated severe hepatitis / 中华围产医学杂志

ABSTRACT

Objective To investigate the incidence and the proper treatment of severe hepatitis during pregnancy. Methods The clinical menifestation and biochemical examination of 29 cases of severe hepatitis during pregnancy were retrospectively analyzed. Results Among 29 cases of severe hepatitis, 7 cases of acute severe hepatitis, 11 subacute severe hepatitis and 11 chronic severe hepatitis were identified. Totally, 2 cases were fully recovered, 13 improved, 5 demised and 5 left without treatment. Fetal death occurred in 1 cases, 2 were stillbirth, and 1 case was neonatal death. The perinatal mortality rate was 43. 8%. Conclusions Severe hepatitis is one of the life-threatening complications during pregnancy. Regular prenatal care and early identification and treatment are crucial to improve the maternal and fetal outcome.