The Effect of Mixed Triamcinolone Acetonide on Prolapsed Lumbar Disc / 中国医师杂志

ABSTRACT

Objective To investigate the therapeutic rate and side effects of different doses of Triamcinolone Acetonide to treat prolapsed lumbar disc. Methods 32 patients with prolapsed lumbar disc were randomly divided into two groups ( n =16). Epidural space was punctured at L3-4 interspace at lateral position, then a epidural catheter was inserted 4 cm distally. 5 min after injection of 3 ml of 1.5% lidocaine, group A or B medication was administered epidurally. Group A contrained Triamcinolone Acetonide 20mg + lidocaine 20mg + vitamin B_ 12 1000?g diluted to 8ml with saline, Group B contained Triamcinolone Acetonide 40mg + lidocaine 20mg + vitamin B_ 12 1000?g diluted to 8ml with saline. The patients were allowed to supine position after 10min in lateral position. 3 injections was made at interval of 3 days, patients were kept in bed for 3 weeks. Results The cure rate at group A and B were 100%. Side effects at group A and B were 31% and 75%, there were statistical significant difference ( P