Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase
Clinical and Molecular Hepatology
;
: 319-325, 2015.
Article
in English
| WPRIM
| ID: wpr-52646
ABSTRACT
The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could be a therapeutic target for liver fibrosis. This review summarizes the role of iNOS in liver fibrosis, focusing on 1) iNOS biology, 2) iNOS-expressing liver cells, 3) iNOS-related therapeutic strategies, and 4) future directions.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Polymorphism, Single Nucleotide
/
RNA, Untranslated
/
Endothelial Cells
/
Nitric Oxide Synthase Type II
/
Hepatic Stellate Cells
/
Kupffer Cells
/
Liver Cirrhosis
/
Nitric Oxide
Limits:
Humans
Language:
English
Journal:
Clinical and Molecular Hepatology
Year:
2015
Type:
Article
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