Significance of combination of serum anti-nucleosome and anti-dsDNA antibodies in patients with systemic lupus erythematosus / 中国医师杂志
Journal of Chinese Physician
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-526492
ABSTRACT
Objective To explore the significance of antinucleosome and anti-dsDNA antibodies on the disease flare and organ damage in patients with systemic lupus erythematosus(SLE).Methods Sixty-nine SLE patients were divided into disease flare group,stable group,lupus nephritis group and non-lupus nephritis group.Serum levels of anti-nucleosome antibody and anti-dsDNA antibody were measured with enzyme linked immunosorbent assay(ELISA) and indirect immunofluorescence(IIF),respectively.Results The positive rates of serum anti-nucleosome and anti-dsDNA antibodies were 55.10% and 47.82% respectively and the rates were significantly higher in disease flare group than those in disease stable group(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Chinese Physician
Year:
2001
Type:
Article
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