Compatible Stability of Gatifloxacin for Injection with Metronidazole Disodium Phosphate / 中国药房

ABSTRACT

OBJECTIVE:To study the compatible stability of gatifloxacin for injection with metronidazole disodium phos-phate in sodium chloride injection.METHODS:The contents of2constituents of the mixed solution stored at25℃within8hours was determined by dual ultraviolet wavelength spectrophotometry,and the appearance,pH value of the mixture were compared with those before.RESULTS:There was no significant change in the content of gatifloxacin after mixing,while the content of metronidazole disodium phosphate has a slight reduction,no significant changes were noted otherwise.CONCLUSI_ ONGatifloxacin for injection is compatible with metronidazole disodium phosphate in sodium chloride injection if at25℃within4hours'mixing.