Significance of polo like kinase1 and protein expression in gastric carcinomas / 中国普通外科杂志

ABSTRACT

Objective To study the significance of polo like kinase1(plk1) mRNA and protein expression in gastric cancer tissues and the relationship between the plk1mRNA and protein expression level in gastric(cancer) tissues and the clinicopathological parameters.Methods Plk1mRNA and protein level were(respectively) measured by real-time PCR and Western blot in fresh tumor tissues and the normal gistric mucosa from 60 patients with gastric cancer.Results plk1mRNA and protein expression level in gastric cancer(tissues) was significantly higher than that in normal gastric tissues(P