The clinical value of multi-tumor markers protein chip assistance diagnostic system in the diagnosis of gastric cancer / 中国医师杂志

ABSTRACT

Objective To investigate the application of multi-tumor markers protein chip diagnostic system in the diagnosis of gastric cancer.Methods Of the 80 patients with gastric cancer,70 patients who suffered from benign digestive disease and 50 healthy persons served as controls.The contents of alpha fetoprotein(AFP),carcinoembryonic antigen(CEA),neuron-specific enolase(NSE),carbohydrate antigen 125(CA125),carbohydrate antigen 153(CA153),carbohydrate antigen 242(CA242),carbohydrate antigen 199(CA199),prostate specific antigen(PSA),free prostate specific antigen(fPSA),ferritin(FER),?-human chorionic gonadotrophin(?-HCG) and human growth hormone(HGH) in the serum of 80 patients with gastric cancer,70 patients with benign digestive disease and 50 healthy persons were determined with multi-tumor markers protein chip assistance diagnostic system and analyzed with statistic method.Results There were 74 patients(92.75%) with tumor makers in serum in 80 cases of gastric cancer,10 cases(14.28%) with tumor makers in 70 cases of benign digestive disease,and 1 case with tumor makers in 50 cases of normal controls.The NSE,HGH,PSA and f-PSA were detected in the serum of partial patients with gastric cancer.Conclusion The application of multi-tumor markers protein chip diagnostic system has certain clinical value in the diagnosis of gastric cancer before surgery.