The methylation of p16 promotor in psoriatic keratinocytes / 中华皮肤科杂志
Chinese Journal of Dermatology
;
(12)1995.
Article
in Chinese
| WPRIM
| ID: wpr-527161
ABSTRACT
Objective To study the relationship between the methylation of p16 promotor and the pathogenesis and progress of psoriasis. Method Methylation-specific PCR and DNA sequencing were used to detect the methylation of p16 promotor. Results The methylation of p16 promotor was found in 23.08% (6/26) of psoriatic lesions and 19.23% (5/26) of non-lesional areas in psoriatic patients, but none in normal controls. The frequency of methylation of p16 promotor was higher in psoriatic lesions than that in normal skin (P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Dermatology
Year:
1995
Type:
Article
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