Effects of sterigmatocystin on IL-4 mRNA expression and protein secretion of murine spleen cells in vitro / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1986.
Article
in Chinese
| WPRIM
| ID: wpr-527176
ABSTRACT
AIM:
To explore the effects of sterigmatocystin (ST) on IL-4 expression and secretion of murine spleen cells in vitro.METHODS:
The secretion and expression of IL-4 in murine spleen cells were studied with ELISA and semi-quantitative RT-PCR method after ST pretreatment at five different dosages (0.125 mg/L, 0.25 mg/L, 0.5 mg/L, 1 mg/L, 2 mg/L) for 2 h and 12 h, respectively.RESULTS:
Semi-quantitative RT-PCR analysis showed that the expression of IL-4 mRNA in ST 0.125, 0.25 and 0.5 mg/L treated groups were higher than that in control group, especially in ST 0.5 mg/L group ( P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1986
Type:
Article
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