Effects of selective cyclooxygenase-2 inhibitor Celebrex on the growth of gallbladder carcinoma GBC-SD cell line / 中国普通外科杂志
Chinese Journal of General Surgery
; (12)1994.
Article
in Zh
| WPRIM
| ID: wpr-527810
Responsible library:
WPRO
ABSTRACT
Objective To investigate the effect of cyclooxygenase-2 inhibitor Celebrex on the growth of(gallbladder) carcinoma GBC-SD cell line.Methods Cell growth suppression was counted by MTT method.Apoptotic index(AI) was evaluated by TUNEL staining.The apoptotic rate was counted by flow cytometry(FCM),fluorescence microscopy(FM) and transmission electron microscopy(TEM).Results Celebrex(inhibiting) the growth of GBC-SD cell line was dose-depend.The growth inhibition rate with 40?mol/L,80?mol/L,120?mol/L and 160?mol/L was 18.77%,25.32%,46.58% and 52.19%(respectively),(P
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of General Surgery
Year:
1994
Type:
Article