Celecoxib induces apoptosis in COX-2 non-expression gastric cancer cells / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Article
in Chinese
| WPRIM
| ID: wpr-527890
ABSTRACT
AIM:
To investigate whether celecoxib induces gastric cancer cell apoptosis in a COX-2 non-expression cell line.METHODS:
The COX-2 protein was examined by western blotting.Fluorescence microscopy,DNA agarose gel electrophoresis and flow cytometry analysis were used to test apoptosis.RESULTS:
COX-2 was expressed in AGS but not MGC-803 gastric cancer cell line;Selective COX-2 inhibitor celecoxib induced MGC-803 cell line apoptosis in a concentration and time-dependent manner.CONCLUSION:
Celecoxib induces apoptosis in COX-2 non-expression gastric cancer cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1989
Type:
Article
Similar
MEDLINE
...
LILACS
LIS