Effects of heterogously-expressed RON receptor tyrosine kinase on motile/invasive ability of human colorectal cancer cell line RKO / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Article
in Chinese
| WPRIM
| ID: wpr-527891
ABSTRACT
AIM:
To investigate the roles of overexpression of RON receptor tyrosine kinase in motile/invasive ability of human colorectal cancer cell line RKO.METHODS:
A eucaryotic expression vector pDR2 containing full-length wt-RON cDNA was transfected into the colorectal cancer cell line RKO and a stable expression clone was obtained.The motile/invasive ability was tested by wound healing test and the transwell migration assay.The expression of E-cadherin was measured by Western blotting.RESULTS:
Motile ability of transfected RKO was greatly promoted by transwell chemotaxis assay(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1989
Type:
Article
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