Changes in circulating endothelial cell numbers and blood lipid levels and their clinical significance in patients with multiple organ dysfunction syndrome / 中国中西医结合急救杂志

ABSTRACT

Objective: To investigate the relationship between circulating endothelial cell(CEC)(numbers),blood lipid levels and multiple organ dysfunction syndrome(MODS) and their clinical(significance).Methods: CECs were separated by isopyknic centrifugation method and blood lipid was(determined) in(35 MODS) patients and 20 healthy controls.CEC numbers and blood lipid were compared in both groups.(Acute) physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) score was recorded to evaluate the severity of the MODS patients.The relationships were analyzed between APACHEⅡ score and CEC numbers,(between) APACHEⅡ and blood lipid levels and between CEC numbers and blood lipid levels.Results: CEC numbers in MODS patients were significantly higher than those in healthy controls(P