Regulatory effects of JNK transduction on interleukin-1?-induced proliferation in rat hepatic stellate cells / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Article
in Chinese
| WPRIM
| ID: wpr-528142
ABSTRACT
AIM:
To study the action of JNK in stimulating proliferation in rat hepatic stellate cells (HSCs) induced by interleukin-1?.METHODS:
Activation of JNK was detected with Western blotting, while the proliferation of HSCs induced by interleukin-1? and the effect of JNK specific blockade SP600125 were measured with cell counting kit-8.RESULTS:
Interleukin-1? up-regulated proliferation in rat HSCs, which was obviously inhibited by SP600125, compared with control group (without SP600125 treatment) (1.560?0.110), the decrease was significant (1.427?0.113, P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1989
Type:
Article
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