Type and cause of liver disease in Korea: single-center experience, 2005-2010
Clinical and Molecular Hepatology
;
: 309-315, 2012.
Article
in English
| WPRIM
| ID: wpr-52818
ABSTRACT
BACKGROUND/AIMS:
The aim of this study was to describe the types and causes of liver disease in patients from a single community hospital in Korea between April 2005 and May 2010.METHODS:
A cohort of patients who visited the liver clinic of the hospital during the aforementioned time period were consecutively enrolled (n=6,307). Consistent diagnostic criteria for each liver disease were set by a single, experienced hepatologist, and the diagnosis of all of the enrolled patients was confirmed by retrospective review of their medical records.RESULTS:
Among the 6,307 patients, 528 (8.4%) were classified as acute hepatitis, 3,957 (62.7%) as chronic hepatitis, 767 (12.2%) as liver cirrhosis, 509 (8.1%) as primary liver cancer, and 546 (8.7%) as a benign liver mass or other diseases. The etiologies in the acute hepatitis group in decreasing order of prevalence were hepatitis A (44.3%), toxic hepatitis (32.4%), other hepatitis viruses (13.8%), and cryptogenic hepatitis (9.1%). In the chronic hepatitis group, 51.2% of cases were attributed to viral hepatitis, 33.3% to nonalcoholic fatty liver disease, and 13.0% to alcoholic liver disease (ALD). Of the cirrhoses, 73.4% were attributable to viral causes and 18.1% to alcohol. Of the hepatocellular carcinoma cases, 86.6% were attributed to viral hepatitis and 11.6% to ALD. Among the benign tumors, hemangioma comprised 52.2% and cystic liver disease comprised 33.7%.CONCLUSIONS:
Knowledge of the current status of the type and cause of liver disease in Korea may be valuable as a basis for evaluating changing trends in liver disease in that country.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Alcohol Drinking
/
Acute Disease
/
Chronic Disease
/
Prevalence
/
Retrospective Studies
/
Cohort Studies
/
Carcinoma, Hepatocellular
/
Fatty Liver
/
Republic of Korea
/
Hepatitis
Type of study:
Etiology study
/
Incidence study
/
Observational study
/
Prevalence study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Clinical and Molecular Hepatology
Year:
2012
Type:
Article
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