Effect of Different Extracting Methods on the Content of Berberine Hydrochloride in Rhizoma Coptis / 中国药房

ABSTRACT

OBJECTIVE:To explore the effect of different extraction methods on the content of berberine hydrochloride in Rhizoma Coptis.METHODS:Berberine hydrochloride in Rhizoma Coptis was extracted respectively by China Pharmacopoeia extraction method,reflux method,ultrasound wave method and refluxing&ultrasonic wave extracting method,and the content of which was determined by HPLC.RESULTS:There were significant differences in the extraction content of berberine hydr_ ochloride between the extraction method stated in China Pharmacopoeia and the other extraction methods(P