Treating Children with Acute Upper Respiratory Infection by Compound Mephedrine Hydrochloride Oral Solution:Survey of 130 Cases / 中国药房

ABSTRACT

OBJECTIVE:To observe the clinical curative efficacy of compound mephedrine hydrochloride oral solution(CMHOS)for acute upper respiratory infection in children.METHODS:A total of240children with acute upper respiratory infection were enrolled:130(treatment group)were randomly assigned to receive ribavirim granules plus CMHOS,and110(control group)to receive ribavirim granules plus amoxicillin granules.Course of treatments for both groups were3days.the severity of symptoms was evaluated by graded scoring system,the symptom changes before and after treatment and the adverse drug reactions were observed.RESULTS:After treatment,both the cure rate and total effective rate were markedly higher in the treatment group than in the control group,with a significantly lower clinical symptoms integral as against the control group.CONCLUSION:The therapy of CMHOS plus ribovirin is effective in treating children with acute upper respiratory in?fection.