Determination of Etoposide in Children with Leukemia by HPLC / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-528345
ABSTRACT
OBJECTIVE:
To establish HPLC method for the determination of plasma etoposide level in children with leukemia.METHODS:
The determination was performed on column Hypersil ODS. The mobile phase was water-methanol (45∶55) and the wavelength for detection was 284nm.RESULTS:
The intraday recovery ranged from 93.56 to 96.24% with SD ranged at 1.07%~2.63%, and the inter-day recovery ranged from 92.85% to 94.26% with SD ranged at 3.55%~5.89%.CONCLUSION:
This method is simple and sensitive, showed a good specificity, and suitable for the determination of etoposide in clinic samples.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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