Improvement in Assay of Cefpodoxime Proxetil by Modified HPLC / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-529265
ABSTRACT
OBJECTIVE:
To modify the HPLC method for determining the contents of cefpodoxime proxetil and cefpodoxime proxetil capsules or suspension,and to compare it with the method of UV determination.METHODS:
ColumnODS-C18,mobile phasemethanol-water(50∶50),flow rate1.5mL?min-1,column temperature40℃,detection wavelength235nm.RESULTS:
The standard curve was rectilinear when cefpodoxime proxetil was within the range of 25~150?g?mL-1(r=0.999 9).The average recovery rate was 98.56%(RSD=1.79%)and the average content of the samples was 101.54%.CONCLUSIONS:
The method is simple,rapid,accurate and sensitive for determination of cefpodoxime proxetil and cefpodoxime proxetil capsules or suspension.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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