Quantitative Determination of Esculetine in Dinglian Tablets by RP-HPLC / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-529679
ABSTRACT
OBJECTIVE:
To establish a RP-HPLC method for the determination of Esculetine in Dinglian tablets.METHODS:
The chromatographic column was Hypersil ODS C18(200mm?4.6mm,5?m)at a temperature of 25℃;the mobile phase was methyl-water-glacial acetic acid(40∶60∶0.4)at a flow velocity of 1.0mL?min-1,and the detection wavelength was set at 353nm.RESULTS:
The linear concentration range of Esculetine was within 0.045~0.360?g(r=0.999 5).The average recovery rate was 97.72%(RSD=1.87%,n=5).CONCLUSION:
This procedure is simple,accurate and reliable,and it can be used for the quality control of Dinglian tablets.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
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