Quantitative Determination of Levofloxacin by PVC Membrane Ion-Selective Electrode / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-529710
ABSTRACT
OBJECTIVE:
To determine the content of levofloxacin by PVC membrane selective electrode.METHODS:
A glass electrode coated with levofloxacin PVC membrane was prepared for the first time with the molecular complex of levofloxacin iodide and bismuth iodide as electric active material, and a series study was performed on its responsibility.RESULTS:
The electrode gave Nernst response to levofloxacin over the concentration range of 5.0?10-3~1.0?10-5 moL?L-1 with a slope rate of 56.5mV?pC-1, a suitable pH of 2.5~4.0, and an average recovery rate of 98.31%~101.6%(2.80%~4.90%).CONCLUSION:
The electrode was simple in operation, and it has a rapid response and good reproducibility, and it is applicable for the quantitative determination of levofloxacin.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
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