The Polymorphism of HindⅢ and PvuII Sites in the Lipoprotein Lipase Gene in Patients with Type 2 Diabetes Mellitus and Insulin Resistance / 中国慢性病预防与控制
Chinese Journal of Prevention and Control of Chronic Diseases
;
(6)2006.
Article
in Chinese
| WPRIM
| ID: wpr-529759
ABSTRACT
Objective To investigate the frequencies of variant of lipoprotein lipase(LPL)gene,HindIII site at intron 8 and PvuII site at intron 6,and its relation with type 2 diabetes mellitus and insulin resistance(IR).Methods PCR-RFLP method was used to determine the DNA polymorphism of 8 th intron and 6 th intron of LPL gene in 78 T2DM patients and 49 controls.Results(1)Compared with control group,the frequencies of H+H+ genotypes and alleles ″H+″ was significantly higher in type 2 diabetes patients(P
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Prevention and Control of Chronic Diseases
Year:
2006
Type:
Article
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