Retrospective Analysis on the Adverse Drug Reactions(ADR) Induced by Second Generation Antihistamine Drugs / 中国药房
China Pharmacy
; (12)2007.
Article
in Zh
| WPRIM
| ID: wpr-529792
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:To analyze the clinical features and correlation factors of ADR caused by second generation antihistamine drugs for references of clinical rational drug use.METHODS:A total of 128 cases ADR cases induced by second generation antihistamine drugs that met our criteria were obtained by retrieving the domestic literature database between 1986 and 2006,which were categorized and analyzed in accordance with the ADR categorization stipulated by WHO international drug monitoring cooperation center.RESULTS:Of the 128 ADR cases,more were seen in male than in female,38 presented cardiovascular system lesions,accounting for 29.69%,followed by lesions of skin and its appendants(28.13%) and systemic reactions(20 cases,15.63%).However,the prognosis of these ADR was satisfactory.CONCLUSION:The ADR caused by second generation antihistamine drugs are associated to many factors such as patients’ sex and physical condition as well as drug combination etc.Clinic should be alert to such ADR such as allergic shock and arhythmia in patients treated with second generation antihistamine drugs.
Full text:
1
Index:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
China Pharmacy
Year:
2007
Type:
Article