Simultaneous Determination of Notoginsenoside R_1 and Ginsenoside Rg_1 in Danqi Tablets by RP-HPLC / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-529839
ABSTRACT
OBJECTIVE:
To develop a RP-HPLC method for the simultaneous determination of Notoginsenoside R1 and Ginsenoside Rg1 in Danqi tablets.METHODS:
The chromatographic separation was performed on a Kromasil C18(250mm?4.6mm,5?m) column with column temperature at room temperature. The mobile phase consisted of acetonitrile-water-H3PO4(20.5∶79.5∶0.02) at a flow rate of 1.0mL?min-1.The detection wavelength was set at 203nm.RESULTS:
The linear range of Notoginsenoside R1 and Ginsenoside Rg1 were 4.67~46.68?g?mL-1 (r=0.999 0) and 4.62~115.50?g?mL-1 (r=0.999 9), respectively; with the average recover of Notoginsenoside R1 at 97.93% and that of Ginsenoside Rg1 at 97.98%, and RSD at 1.31%(n=6) and 1.38%(n=6), respectively.CONCLUSION:
The method is simple, rapid and accurate, and suitable for the quality control of Danqi tablets.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
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