Determination of Phospholipid Content in 5-FUR Prodrug Liposome / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-530158
ABSTRACT
OBJECTIVE:
To determine the concentration of phospholipid in 5-FUR prodrug liposome.METHODS:
The sample was fragmented by ethanol and extracted by chloroform. The concentration of phospholipid in 5-FUR prodrug liposome was determined by ammonium ferrothiocyarate spectrophometry at a wavelength 488 nm.RESULTS:
The linear range of phospholipid was 0.01~0.10 mg?mL-1(r=0.999 6, n=3) with an average recovery rate of 99.66% (RSD=3.17%).CONCLUSION:
This method is simple, convenient and sensitive, and it can be used for the quality control of 5-FUR prodrug liposome.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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