Determination of the Dissolution of Perospirone Hydrochloride Tablets / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-530629
ABSTRACT
OBJECTIVE:
To establish a method for the determination of the dissolution of perospirone hydrochloride tablets(PHT).METHODS:
The dissolution of PHT was determined in accordance with Chinese Pharmacopeia(2005 Edition) using water as solvent with the rotation speed at 50 r?min~(-1).The sample was taken at 30 minutes with its absorbability detected at a wavelength of 316 nm determinated by UV.Then the dissolution was calculated.RESULTS:
The linear range of perospirone hydrochloride was 2~20?g?mL~(-1)(r=0.999 9)with an average recovery at 99.76%(RSD = 0.27%).The dissolutions of 3 batches of samples were all above 80%.CONCLUSION:
The method was proved to be simple and reliable, and it can be used to determine the dissolution of PHT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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