Site specific antibody of Na/Ca exchanger stimulates Na/Ca exchanger current and has cross-reaction with Ca channel and Na pump / 中国病理生理杂志
Chinese Journal of Pathophysiology
;
(12)1989.
Article
in Chinese
| WPRIM
| ID: wpr-530632
ABSTRACT
1∶640) was purified by affinity chromatography with a Mab Trap kit.The effects of the purified IgGs on the ion channel and transporter(INa/Ca,INa pump,ICa-L,Itko,Ik1,IK) at concentrations of 10 nmol/L,20 nmol/L and 40 nmol/L were observed by whole cell voltage clamp technique.RESULTS:
The purified IgG enhanced INa/Ca,ICa-L and I Na/k pump in a dose-dependent manner and no significant effect on INa,Itko,Ik1 and Ik was found.CONCLUSION:
The site specific antibody of Na-Ca exchanger stimulates Na-Ca exchanger current and has cross-reaction with L-type Ca channel and Na pump.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Pathophysiology
Year:
1989
Type:
Article
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