Protective Effects of Fucose and Vitamin E on Immune Suppression Caused by Chemotherapy in Model Mice / 中国慢性病预防与控制
Chinese Journal of Prevention and Control of Chronic Diseases
;
(6)2006.
Article
in Chinese
| WPRIM
| ID: wpr-530637
ABSTRACT
Objective To explore the protective effects of the combination of fucose and vitamin E on immune suppression caused by chemotherapy in model mice.Methods firstly,the model mice with lung adenoma were induced by urethane.Then the combination of fucose and vitamin E were administered to the mice after taking chemotherapy.T lymphocyte subpopulation and interleukin-2 concentration were detected by FCM to observe the change of immune function of the mice.Results Compared with chemotherapy control group,the combination of fucose and vitamin E could increase the percent of CD3+,CD4+,ratio of CD4+/CD8+ and the concentration of interleukin-2,but decrease the percent of CD8+.Conclusion The combination of fucose and vitamin E can obviously reduce the immune suppression caused by chemotherapy in mice.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Prevention and Control of Chronic Diseases
Year:
2006
Type:
Article
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