Effects of Different Hypoglycemic Drugs on QT Interval Dispersion in Patients with Type 2 Diabetes Mellitus / 中国药房
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-530705
ABSTRACT
OBJECTIVE:
To investigate the effects of different kinds of hypoglycemic drugs on the QT interval dispersion in patients with type 2 diabetes mellitus.METHODS:
The differences of QT interval dispersion (QTd) and corrected QT interval dispersion (QTcd) in 318 patients with type 2 diabetes (of which, 129 were assigned to receive insulin, 110 glibenclamide and 79 metformin) and 33 healthy volunteers (normal control) were compared.RESULTS:
The QTd and QTcd were all significantly higher in glibenclamide group than in the other three groups(P0.05).CONCLUSION:
The results suggest that glibenclamide and insulin may increase the QTd and QTcd in patients with type 2 diabetes.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2005
Type:
Article
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