Effects of Enalapril and Irbesartan on the Expression of Related Plasma Molecule-marker / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-531379
ABSTRACT
OBJECTIVE:
To investigate the effects of irbesartan and enalapril on the blood pressure and the expression of related plasma molecule-marker in SHR rats.METHODS:
Forty SHR were randomly divided into irbesartan group(SHR-I),enalapril group(SHR-E),irbesartan-enalapril group(SHR-IE) and blank control group(SHR-C).Another ten WKY rats were assigned to normal group(WKY).The blood pressure and activities of sICAM-1 and PAI-1 were measured after 16-week's intragastric administration with corresponding drugs,and then the results were compared with those before experiment.RESULTS:
As compared before treatment,there were significant differences in blood pressure in all drug-treated groups after treatment(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
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