Investigation of the correlation between a group of metastasis-associated proteins and metastatic potency in breast carcinoma / 中国普通外科杂志
Chinese Journal of General Surgery
; (12)2000.
Article
in Zh
| WPRIM
| ID: wpr-531416
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ABSTRACT
Objective To investigate the expression and the significance of a group of metastasis-associated proteins in invasive ductal breast carcinoma(IDC).Methods Tissue microarray containing 247 IDC specimens was constructed.The expressions of ?-B crystallin,CD44v6,MMP-2 and TIMP-2 were detected by immunohistochemistry,and the relation between the expression of these proteins and the clinicopathologic character was analyzed.Results(1) The expression rates of ?-B crystallin,CD44v6,MMP-2 and TIMP-2 in IDC were 70.0%,61.5%,57.5% and 57.1% respectively,and significantly higher than those of normal breast tissues(P
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of General Surgery
Year:
2000
Type:
Article