Study on Quantitative Detection of Bacterial Endotoxins in Methylthioninium Chloride Injection / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-531487
ABSTRACT
OBJECTIVE:
To establish a method for detecting bacterial endotoxins in methylthioninium chloride injection (MCI) quantitatively.METHODS:
Kinetic turbidimetric limulus test was applied to detect bacterial endotoxins in MCI quantitatively, and compared with gel-clot method.RESULTS:
MCI was un-interfered with the test for bacterial endotoxins at the concentration of 0.125 mg?mL-1; the content of bacterial endotoxins in all samples tested (10 mg?mL-1) were not more than 0.25 EU?mg -1, which were in accordance with the result of gel-clot method.CONCLUSIONS:
Kinetic turbidimetric limulus test provides a new way to detect bacterial endotoxins in MCI quantitatively.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS