Effect of Shuanghuang Tongfeng Capsules on Experimental Gouty Arthritis / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-531627
ABSTRACT
OBJECTIVE:
To observe the effect of Shuanghuang tongfeng capsule(SHTF) on the gouty arthritis.METH-ODSThe gouty arthritis model of rats and rabbits were induced using sodium urate(MSU). The swollen degree of the rat foot,and the amount of synovial fluid,the leucocyte count in synovial fluid and the degree of inflammation of the synovial tissue of joints in rabbits were measured.The effect of SHTF on gouty arthritis was observed.RESULTS:
The swollen degree of the foot of rat was lessened obviously by SHTF capsule(5、10、20 g?kg-1,ig).The amount of synovial fluid and the leucocyte count in synovial fluid of the rabbit were decreased significantly by SHTF capsule (4、8、16 g?kg-1,po).The inflammation of the synovial tissue in rabbits was improved obviously by SHTF capsule (8 and 16 g?kg-1,po).CONCLUSION:
SHTF capsule have remarkable protective effect on the gouty arthritis induced by sodium urate.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
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