Content Determination of Main Compontents in Haloperidol Tablets by HPLC / 中国药房
China Pharmacy
;
(12)1991.
Article
in Chinese
| WPRIM
| ID: wpr-531769
ABSTRACT
OBJECTIVE:
To develop an HPLC method for determination of the content of the main compontents in haloperidol tablets.METHODS:
The samples were determined on Diamonsil C18 column at a column temperature of 35 ℃. The mobile phase consisted of 0.1 mol?L-1 K2HPO4 (pH 3.0)-methanol (45∶55) at a flow rate of 1.0 mL?min-1. The UV detection wavelength was 248nm and the sample size was 20 ?L.RESULTS:
The linear range for haloperidol was 0.01~1 mg?mL-1 (r=0.999 9) and its average recovery was 97.6% (RSD=1.1%).CONCLUSIONS:
The method was simple, rapid, accurate and specific, and suitable for the quality control of this preparation.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
1991
Type:
Article
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