The diagnosis and treatment of acute pancreatitis during pregnancy:a report of 48 cases / 中国普通外科杂志

ABSTRACT

Objective To study the clinical characters,diagnosis and principles of treatmentof acute pancreatitis during pregnancy.Methods Forty-eight cases of acute pancreatitis during pregnancy treated in the recent 8 years were retrospectively analyzed,38 cases had non-surgical treatment(of which 36 cases were cured);10 cases had surgical treatment to remove necrotic tissue and mainly termination of pregnancy.Results Most of the cases in this group had simple pancreatitis,which accounted for 64.58%(31/48).There were 5 cases of maternal(10.42%) death and three cases of fetal(6.25%) death,and all were in patients with severe pancreatitis.Fatality rate of pregnant women with severe pancreatitis was 29.41%.Conclusions Acute pancreatitis during pregnancy is a serious disease with low prevalence rate,but has high fatality rate,and is the primary cause of death in acute abdomen of pregnancy.Nonoperative treatment is the first choice of treatment in this condition.In severe cases,timely surgical intervention is warranted,and the surgical indications should not be altered because of the pregnancy.The safety of both the pregnant woman and the fetus must simultaneously be kept into mind during therapy.