The expression of COX-2 and VEGF in laryngeal carcinoma tissue and its clinical significance / 中国耳鼻咽喉头颈外科
Article
in Zh
| WPRIM
| ID: wpr-532014
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WPRO
ABSTRACT
OBJECTIVE To investigate the expression of Cyclooxygenase-2(COX-2)andVascular endothelial growth factor(VEGF)in laryngeal carcinoma tissue and its clinical significance. METHODS Sixty-five samples of laryngeal carcinoma and thirty-four biopsies of adjacent noncancerous tissue were immunohistochemically examined for expression of COX-2 and VEGF, whose relationship with clinicopathological parameters was also analysied. RESULTS Percentages of COX-2 and VEGF expression in laryngeal carcinoma tissue were 63.08% and 70.77% respectively, which were higher than those in adjacent noncancerous tissue(P
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WPRIM
Language:
Zh
Journal:
Chinese Archives of Otolaryngology-Head and Neck Surgery
Year:
2006
Type:
Article