Stability of Biyuanling Granules / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-532204
ABSTRACT
OBJECTIVE:
To study the stability of Baicalin in Biyuanling granules and predicate its validity duration.METHODS:
The content of Baicalin in Biyuanling granules was determined by RP HPLC on Diamonsil ODS C_(18) chromatographic column(200 mm?4.6 mm,5?m) with methanol -water- phosphoric acid(53470.2) used as mobile phase.The detective wavelength was set at 274 nm.The stability of Baicalin in Biyuanling granules was determined by classical accelerated test process in constant temperature and its validity duration was computed.RESULTS:
The disintegration constant of Baicalin at 25℃was K = 4.592?10 ~6 h~1,and the validity duration was t_(0.9)=2.62 years.CONCLUSION:
The method developed in this study was proved to be scientific,reasonable and suitable for the study of the stability of Biyuanling granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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