Effect of Jiedu Quyu Formula for Psoriasis Vulgaris and Its Influence on Plasma Endothelin / 中医杂志

ABSTRACT

Objective To study the therapeutic effect of Jiedu Quyu Formula (Formula for Removing Toxins and Blood Stasis) on psoriasis vulgaris of progressive stage and its mechanism. Methods The 70 patients of progressive psoriasis vulgaris were randomized into treatment group (35 cases), treated by Jiedu Quyu Formula, and control group (35 cases), treated by Compound Qingdai Capsule. Healthy control group was of 30 healthy subjects. The contents of plasma endothelin (ET) were determined before and after treatment respectively, and the therapeutic effect of both treated groups were observed. Results After treatment, the psoriasis area and severity index (PASI) of both treated groups were significantly decreased in comparison with before treatment (P