Compatible Stability of Gatifloxacin for Injection with Cefmetazole for Injection / 中国药房

ABSTRACT

OBJECTIVE:To study the compatible stability of gatifloxacin for injection with cefmetazole for injection in 0.9% sodium chloride injection versus in 5% glucose injection.METHODS:The changes in appearance and pH value and UV absorption spectra for the mixture of gatifloxacin for injection with cefmetazole for injection at room temperature(20?1)℃ with 8 hours were observed,and the contents of gatifloxacin and cefmetazole were determined by dual ultraviolet spectrophotometry.RESULTS:No marked change was noted for the mixture within 8 hours in appearance,pH value,contents and UV peak shape.CONCLUSION:Gatifloxacin for injection is compatible with cefmetazole for injection in 0.9% sodium chloride injection or 5% glucose injection.