Characteristics of Myocardial Deformation and Rotation in Subjects With Diastolic Dysfunction Without Diastolic Heart Failure
Korean Circulation Journal
;
: 532-537, 2009.
Article
in English
| WPRIM
| ID: wpr-53257
ABSTRACT
BACKGROUND AND OBJECTIVES:
There have been very few pathophysiologic studies on isolated diastolic dysfunction. We hypothesized that the characteristics of isolated diastolic dysfunction would be located, on the clinical continuum, between those of a normal heart and diastolic heart failure. SUBJECTS ANDMETHODS:
We enrolled 102 subjects who had no history of overt symptoms of heart failure and who had a left ventricular ejection fraction of more than 50%. They were examined for myocardial deformation and rotation using the two-dimensional speckle tracking image (2D-STI) technique.RESULTS:
The circumferential strains and radial strain at the apical level (RS(apex)) were related to the ratio of the transmitral early peak velocity over the early diastolic mitral annulus velocity (E/E'). After adjustment for age, the RS(apex) showed a positive relationship with the E/E' ratio; whereas, the circumferential strains did not. Instead, the circumferential strains demonstrated a significant correlation with age. Basal rotation and left ventricular (LV) torsion were also related to age, but had no relationship with the E/E' ratio. However, as the E/E' ratio value increased, systolic mitral annular velocity decreased.CONCLUSION:
Except for the RS(apex), LV myocardial deformation and rotation did not vary with the degree of E/E' ratio elevation when there was no associated diastolic heart failure. Additionally, in clinical situations such as isolated diastolic dysfunction, the advancement of age has a relatively greater influence on characteristics of LV myocardial deformation and rotation rather than on the E/E' ratio.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sprains and Strains
/
Stroke Volume
/
Track and Field
/
Echocardiography, Doppler
/
Heart Failure, Diastolic
/
Heart
/
Heart Failure
Language:
English
Journal:
Korean Circulation Journal
Year:
2009
Type:
Article
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