Effect of Benazepril and Candesartan Combination for Treatment of Hypertension With Microalbuminuria / 中国循环杂志
Chinese Circulation Journal
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-532738
ABSTRACT
Objective:
To compare the effect between benazepril and candesartan combination and single medication in either one of them for treatment of hypertension-combined with microalbuminuria(MCA).Methods:
A total of 95 patients were divided into three groups.Benazepril group(n=31),patients were treated with Benazepril 10~20 mg/day;Candesartan group(n=32),patients were treated with Candesartan 4~8 mg/day;and Combination group (n=32),patients were treated with benazepril 10 mg/day and candesartan 4 mg/day.The medication lasted for 8 weeks.Blood pressure(BP),plasma urinary albumin and creatinine ratio(A/C),endothelin-1(ET-1),nitrogen monoxide(NO)and potassium were examined and compared before and after the medication respectively.Results:
The levels of BP,plasma A/C and ET-1 were decrease and NO was increased in all three groups(P0.05,respectively).Conclusion:
Effect of benazepril and candesartan combination in patients with hypertension-combined microalbuminuria was better than single medication in either benazepril or candesartan.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2005
Type:
Article
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