Expression and significance of aquaporin-1 in breast carcinoma / 中国普通外科杂志

ABSTRACT

Objective To explore the expression and the significance of aquaporin 1(AQP1) in breast carcinoma tissues.Methods Specimcns of breast carcinoma tissues of 40 cases and the non-cancerous adjacent tissues of 10 cases were obtained immediately after surgery,and expression of aquaporin1 in htese tissues was examined by RT-PCR technique.Results AQP1mRNA expression level in breast tumor tissues was 0.8957?0.0428,that in non-cancerous adjacent tissues was 0.3401?0.0549,and there was significant difference between them(P