Clinical analysis on the main early postoperative complications of pancreatoduodenectomy / 中国普通外科杂志

ABSTRACT

Objective To summarize the main early complications after pancreatoduodenectomy and analysis of the probable causes.Methods The clinical data of 576 cases who underwent pancreatoduodenectomy(PD) in our department between Feb 1990 and May 2009 were analysed retrospectively.Results There were 92 early postoperative complications occurred in 85 patients(14.8%).Gastrointestinal dysfunction,pancreatic leakage,intra-abdominal infections and hemorrhage were the most of complications,and 7 cases died during perioperative period(mortality 1.22%),among which 3 died of multiple system organ failure,2 died of hemorrhagic shock and 2 died of toxic shock.Preoperative hypoproteinemia and hyperbilirubinemia complicated with a high incidence of postoperative complications on multivariate analysis.Conclusions Meticulous preoperative preparation,delicate intraoperative technigne and close postoperative observation are the key points to decrease early complications and improve the prognosis of the patients who undergo PD.