Effect of Bushen Qiangdu Formula on Serum Osteoprotegerin,Bone Mineral Density and Bone Metabolism of 50 Patients of Osteoporosis with Ankylosing Spondylitis / 中医杂志

ABSTRACT

Objective To study the effect of and its mechanism Bushen Qiangdu Formula (Formula for reinforcing kidney and strengthening spine) on patients with osteoporosis induced by ankylosing spondylitis (AS).Methods All 50 AS patients with osteoporosis were treated with Bushen Qiangdu Formula for six months.Before and after treatment,the observation term includes serum osteoprotegerin (OPG),bone mineral density (BMD),serum boneglaprotein (BGP),calcitonin (H-CT),parathyroid hormone (PTH),bone-specific alkaline phosphatase (BAP),collagen I carboxyl-terminal-prolonging peptides (CICP),urine deoxidation pydidinoline (DPD),C-telopeptide of type I collagen (CTX-I),erythrocyte sedimentation rate (ESR),C reactive protein (CRP),Bath AS Function Index (BASFI),Bath AS dynamic Index (BASDI),and symptoms and signs.Results After treatment,the serum OPG significantly increased (P