Quantified Grading of TCM Syndrome Manifestations of Cerebral Infraction / 中医杂志

ABSTRACT

Objective To explore the standard of quantified grading of TCM syndrome manifestations of cerebral infraction.Methods The epidemiological investigation was carried out in the 841 cases of cerebral infarction with different TCM syndrome manifestations. The data obtained was analyzed with the step discriminant method of multivariate statistical analysis to build up the distinction equation mathematical expression. Self-validation, cross-validation, and prospective validation were applied to verify this grading and standard grading. Results Corss-validation the Kappa coefficient of wind and blood stasis syndrome, qi deficiency syndrome, phlegm damp syndrome, fire heat syndrome, and yin deficiency syndrome was 0.919, 0.896, 0.872, 0.786, and 0.888 respectively. Prospective validation the Kappa coefficient of wind and blood stasis syndrome, qi deficiency syndrome, and phlegm damp syndrome was 0.987, 0.757, and 0.795 respectively. The distinction equation mathematical expressions and scales of mild, medium, and severe cases of all syndromes of cerebral infarction were established.Conclusion The expressions created in this study were stable and qualified clinical practice well. The grading diagnosis based on these expressions was repeatable and provided the practical mathematical method for quantified grading of cerebral infraction.