Study on the Activity of Flavonoids Extracted from Mallotus apelta against Duck Hepatitis B Virus / 中国药房
China Pharmacy
;
(12)2001.
Article
in Chinese
| WPRIM
| ID: wpr-533564
ABSTRACT
OBJECTIVE:
To study the activity of flavonoids WF extracted from Mallotus apelta against duck hepatitis B virus (DHBV).METHODS:
One-day-old ducklings were infected with DHBV.7 days later the DHBV-infectious model was established successfully.The model ducklings were administrated with WF of 75 and 150 mg?kg-1 or lamivudine of 50 mg?kg-1 b.i.d.via i.g.gtt for 10 days consecutively.Serums were collected at 5th and 10th day after drug administration and 3th days after drug withdrawal.The level of DHBV-DNA in serum was detected by dot-blotting hybridization test.RESULTS:
75 and 150 mg?kg-1 WF reduced the level of DHBV-DNA significantly(P
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2001
Type:
Article
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