Clinical Observation of Qianggan Capsule in the Treatment of Nonalcoholic Fatty Liver Fibrosis / 中国药房

ABSTRACT

OBJECTIVE:To observe the efficacy of Qianggan capsule in the treatment of nonalcoholic fatty liver.METHODS:28 patients with nonalcoholic fatty liver disease were randomly divided into experimental group (n=16) and control group (n=12).Both groups were given basic treatment of hepatoprotective drug for six months.Experimental group were treated with Qianggan capsule additionally.Clinical symptom,hepatic function,the biomarkers of oxidative stess,hepatic fibrosis indicators of 2 groups' before and after treatment were observed as well as liver biopsy.RESULTS:As compared with before treatment,experimental group were improved significantly in respects of GSH-PX,SOD,MDA,HA,PcⅢ,ⅣC,LN,TIMP-1,histopathological score (P