Dissolution Determination of Erythromycin Ethylsuccinate Granules / 中国药房
China Pharmacy
;
(12)2007.
Article
in Chinese
| WPRIM
| ID: wpr-533628
ABSTRACT
OBJECTIVE:
To establish a method for dissolution determination of Erythromycin ethylsuccinate granules.METHODS:
Paddle method was adopted and 0.1 mol?L-1 HCl solution was used as dissolution medium at rotation rate of 50 r?min-1.UV spectrophotometry was used to detect at wavelength of 482 nm.Dissolution rate was calculated.RESULTS:
The linear range of erythromycin ethylsuccinate were 4~40 mg?L-1(r=0.999 0,n=5)with an average recovery of 99.19%(RSD=0.56%).Dissolution rate of erythromycin ethylsuccinate was more than 80% within 30 min.CONCLUSION:
The method is rapid,simple and accurate for the quality control of Erythromycin ethylsuccinate granules.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2007
Type:
Article
Similar
MEDLINE
...
LILACS
LIS