Cardiovascular Drugs-induced ADR of Our Hospital during 2003～2008: An Analysis of 215 Cases / 中国药房

ABSTRACT

OBJECTIVE: To probe into the status quo of cardiovascular drug-induced ADR and to provide reference for clinical utilization and ADR monitoring. METHODS: A total of 215 ADR cases of our hospital during 2003～2008 collected from electronic reporting system were classified, analyzed and evaluated. RESULTS: 84 kinds of drugs were involved, of which adrenergic agent occupied the dominant place (n=78), followed by calcium antagonists, anticoagulant, fibrinolytic agents and AT1R bloker. 18 cases induced by TCM involved 9 kind of Chinese patent drug. The first 3 drugs that involved in term of frequency of ADR were buflomedil, amlodipine and alprostadil. The main clinic manifestations of ADRs were lesion of skin and its appendants, psychological system and digestive system. CONCLUSION: More attention should be paid to safety of long-term prescription in such chronic disease and cardiovascular drug-induced ADR monitoring.