Protection Effect of Fritillaria thunbergii against Hyperthyroidism in Rats and Mice / 中国药房

ABSTRACT

OBJECTIVE:To study the protection effect of Fritillaria thunbergii against hyperthyroidism in rats and mice. MET-HODSHyperthyroidism rats and mice were induced with thyrine. The effect of F. Thunbergii on T3,T4,cAMP,cGMP and hypoxia tolerance were observed. RESULTS:F. Thunbergii can decrease T3,T4 and cAMP of rats significantly. It also can increase the abi-lity of hypoxia tolerance of mice significantly. CONCLUSION:F. Thunbergii has sound effect on hyperthyroidism.